Molecular Landscape for Malignant Transformation in Diffuse Astrocytoma
نویسندگان
چکیده
منابع مشابه
Hemorrhagic Recurrence in Diffuse Astrocytoma without Malignant Transformation
Although uncommon, hemorrhage can be a complication of low grade glioma with an unfavorable prognosis such as transformation to higher grade glioma. To our knowledge, hemorrhagic recurrence of World Health Organization Grade II, diffuse astrocytoma without malignant transformation has not been reported. Thus, we report a case of diffuse astrocytoma with hemorrhagic recurrence without malignant ...
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Pilocytic astrocytoma (PA) is a circumscribed neoplasia considered as a grade I astrocytoma by the World Health Organization. Its most common location is the cerebellum and it develops during the first two decades of the life. Prognosis is mostly excellent if gross-total resection can be achieved, with 10-year survival rates of up to 80%. Anaplastic or malignant transformation (MT) can rarely o...
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Pilocytic astrocytoma is a slowly growing neoplasia that represents the most frequent cerebral tumor in pediatric age. Malignant transformation is rare and it is usually related to previous radiotherapy. The authors describe a case of a spontaneous malignant transformation of a pilocytic astrocytoma. A 3-year-old boy was diagnosed with a cerebellar hemisphere tumor. He was submitted to a comple...
متن کاملMolecular markers relating to malignant progression in Grade II astrocytoma.
OBJECT Astrocytoma may progress rapidly or remain stable for many years. To clarify whether molecular characteristics could be prognostic factors, several cell cycling-associated molecular alterations in the diffuse astrocytoma have been investigated. METHODS Thirty-three patients in whom WHO Grade II astrocytoma had been initially diagnosed were assigned to 1 of 3 groups. Group 1 consisted o...
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Running title: Targeting BRAF V600E in Malignant Astrocytoma We declare no conflict of interest (or relationship that would be suspected of constituting conflicts) at the time of submission. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Malignant astrocytoma (MA) is the most common histopathologic subclassification for primary central nerv...
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ژورنال
عنوان ژورنال: Global Medical Genetics
سال: 2021
ISSN: 2699-9404
DOI: 10.1055/s-0041-1731069